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About
Pronouns: She/Her/Hers
Languages: English, Mandarin, Spanish
Biographical Sketch:
Tiffany Kuo grew up in Taiwan and graduated from the University of California, San Diego (UCSD) in 2020 with a BS in Biochemistry and Cell Biology and a minor in Cognitive Science. At UCSD, she worked with Dr. Sonya Neal on studying the cellular response to the accumulation of misfolded membrane proteins in Saccharomyces cerevisiae (S. cerevisiae).
She began her PhD studies at Northwestern University's Interdisciplinary Biological Sciences Graduate Program (IBiS) in 2021 and joined Dr. Vadim Backman's research lab to investigate the interplay between chromatin conformation, genome connectivity, and transcription in a gene-specific manner. She is also a trainee in the National Institutes of Health (NIH) Physical Genomics Training Program (NIH T32).
Outside of the lab, Tiffany enjoys reading, traveling, and binge-watching reality television shows.
Awards and Honors:
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Introduction to Graduate Education at Northwestern University (IGEN) Scholar, October 2020
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Triton Research and Experiential Learning Scholar (TRELS), University of California, San Diego (UCSD), March 2020
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Ledell Family Research Scholarship for Science and Engineering, University of California, San Diego (UCSD), June 2019
Selected Works:
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Shim, A. R., Frederick, J., Pujadas, E. M., Kuo, T., Ye, I. C., Pritchard, J. A., ... & Backman, V. (2024). Formamide Denaturation of Double-Stranded DNA for Fluorescence in Situ Hybridization (FISH) Distorts Nanoscale Chromatin Structure. PLoS One, 19(5), e0301000.
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Kandel, R., Jung, J., Syau, D., Kuo, T., Songster, L., Horn, C., ... & Neal, S. E. (2023). Yeast Derlin Dfm1 Employs a Chaperone-like Function to Resolve Misfolded Membrane Protein Stress. PLoS Biology, 21(1), e3001950.
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Nejatfard, A., Wauer, N., Bhaduri, S., Conn, A., Gourkanti, S., Singh, N., Kuo, T., ... & Neal, S. E. (2021). Derlin Rhomboid Pseudoproteases Employ Substrate Engagement and Lipid Distortion to Enable the Retrotranslocation of ERAD Membrane Substrates. Cell Reports, 37(3).